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Single-Molecule Fluorescence Using Nucleotide Analogs: A Proof-of-Principle

[Image: see text] Fluorescent nucleotide analogues, such as 2-aminopurine (2AP) and pyrrolo-C (PyC), have been extensively used to study nucleic acid local conformational dynamics in bulk experiments. Here we present a proof-of-principle approach using 2AP and PyC fluorescence at the single-molecule...

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Hlavní autoři: Alemán, Elvin A., de Silva, Chamaree, Patrick, Eric M., Musier-Forsyth, Karin, Rueda, David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985717/
https://ncbi.nlm.nih.gov/pubmed/24803990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz4025832
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