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A ribozyme that triphosphorylates RNA 5′-hydroxyl groups

The RNA world hypothesis describes a stage in the early evolution of life in which RNA served as genome and as the only genome-encoded catalyst. To test whether RNA world organisms could have used cyclic trimetaphosphate as an energy source, we developed an in vitro selection strategy for isolating...

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Hlavní autoři: Moretti, Janina E., Müller, Ulrich F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985629/
https://ncbi.nlm.nih.gov/pubmed/24452796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1405
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