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Quantitative Analysis of rRNA Modifications Using Stable Isotope Labeling and Mass Spectrometry

[Image: see text] Post-transcriptional RNA modifications that are introduced during the multistep ribosome biogenesis process are essential for protein synthesis. The current lack of a comprehensive method for a fast quantitative analysis of rRNA modifications significantly limits our understanding...

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Detalhes bibliográficos
Main Authors: Popova, Anna M., Williamson, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985470/
https://ncbi.nlm.nih.gov/pubmed/24422502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja412084b
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