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Analgesic efficacy of buprenorphine in the presence of high levels of SDF-1α/CXCL12 in the brain

Although morphine is often the best option for treating acute and chronic severe pain, its analgesic activity can be blocked in situations in which there are elevated levels of chemokines. Indeed, recently we have shown that elevated brain levels of the chemokine stromal cell-derived growth factor-1...

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Bibliografische gegevens
Hoofdauteurs: Benamar, Khalid, Palma, Jonathan, Cowan, Alan, Geller, Ellen B., Adler, Martin W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985345/
https://ncbi.nlm.nih.gov/pubmed/21112161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2010.08.015
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