Determination of Acid Dissociation Constants (pK(a)) of Bicyclic Thiohydantoin-Pyrrolidine Compounds in 20% Ethanol-Water Hydroorganic Solvent

The acid dissociation constants of potential bioactive fused ring thiohydantoin-pyrrolidine compounds were determined by potentiometric titration in 20% (v/v) ethanol-water mixed at 25 ± 0.1°C, at an ionic background of 0.1 mol/L of NaCl using the HYPERQUAD computer program. Proton affinities of pot...

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Bibliographic Details
Main Authors: Nural, Yahya, Döndaş, H. Ali, Sarı, Hayati, Atabey, Hasan, Belveren, Samet, Gemili, Müge
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985308/
https://ncbi.nlm.nih.gov/pubmed/24799905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/634194
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