Single Ascending Dose Safety and Pharmacokinetics of CDRI-97/78: First-in-Human Study of a Novel Antimalarial Drug

Background. CDRI 97/78 has shown efficacy in animal models of falciparum malaria. The present study is the first in-human phase I trial in healthy volunteers. Methods. The study was conducted in 50 healthy volunteers in a single, ascending dose, randomized, placebo-controlled, double blind design. T...

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Detalhes bibliográficos
Main Authors: Shafiq, N., Rajagopalan, S., Kushwaha, H. N., Mittal, N., Chandurkar, N., Bhalla, A., Kaur, S., Pandhi, P., Puri, G. D., Achuthan, S., Pareek, A., Singh, S. K., Srivastava, J. S., Gaur, S. P. S., Malhotra, S.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985299/
https://ncbi.nlm.nih.gov/pubmed/24800100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/372521
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