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Characterization of synthetic oligonucleotides containing biologically important modified bases by MALDI-TOF mass spectrometry

Oligonucleotides containing modified bases are commonly used for biochemical and biophysical studies to assess the impact of specific types of structural damage on DNA structure and function. In contrast to the synthesis of oligonucleotides with normal DNA bases, oligonucleotide synthesis with modif...

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Detalhes bibliográficos
Main Authors: Cui, Zhengfang, Theruvathu, Jacob A., Farrel, Alvin, Burdzy, Artur, Sowers, Lawrence C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985270/
https://ncbi.nlm.nih.gov/pubmed/18485883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.04.031
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