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Cytochrome C and Caspase-3/7 are Involved in Mycophenolic Acid- Induced Apoptosis in Genetically Engineered PC12 Neuronal Cells Expressing the p53 gene

Mycophenolic acid (MPA) is the active metabolite of mycophenolate mofetil. This study designed to investigate the mechanism of cytotoxicity of MPA on the genetically engineered PC12 Tet Off (PTO) neuronal cells with p53 gene. Alamar Blue (AB) reduction showed concentration-dependent cytotoxicity of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Malekinejad, Hassan, Moradi, Masumeh, Fink-Gremmels, Johanna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Shaheed Beheshti University of Medical Sciences 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985263/
https://ncbi.nlm.nih.gov/pubmed/24734071
Tagiau: Ychwanegu Tag
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