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Mining a database of single amplified genomes from Red Sea brine pool extremophiles—improving reliability of gene function prediction using a profile and pattern matching algorithm (PPMA)

Reliable functional annotation of genomic data is the key-step in the discovery of novel enzymes. Intrinsic sequencing data quality problems of single amplified genomes (SAGs) and poor homology of novel extremophile's genomes pose significant challenges for the attribution of functions to the c...

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Hlavní autoři: Grötzinger, Stefan W., Alam, Intikhab, Ba Alawi, Wail, Bajic, Vladimir B., Stingl, Ulrich, Eppinger, Jörg
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985023/
https://ncbi.nlm.nih.gov/pubmed/24778629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00134
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