Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer's disease

Alzheimer's disease (AD) is a complex disorder that affects the central nervous system causing a severe neurodegeneration. This pathology affects an increasing number of people worldwide due to the overall aging of the human population. In recent years SUMO protein modification has emerged as a...

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Detalhes bibliográficos
Main Authors: Nisticò, Robert, Ferraina, Caterina, Marconi, Veronica, Blandini, Fabio, Negri, Lucia, Egebjerg, Jan, Feligioni, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985012/
https://ncbi.nlm.nih.gov/pubmed/24778618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00063
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