HIF-1α had Pivotal Effects on Downregulation of miR-210 Decreasing Viability and Inducing Apoptosis in Hypoxic Chondrocytes

Hypoxia-inducible factor 1-alpha (HIF-1α) and some microRNA (miRNAs) play pivotal roles in response to hypoxia-related physiologic and pathophysiologic responses. Up to date, the regulatory mechanisms of these molecules were largely unknown in chondrocytes. In this study, to study the mechanisms of...

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Autors principals: Chang, Zhiqiang, Huo, Lifeng, Wu, Yimin, Zhang, Pei
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984849/
https://ncbi.nlm.nih.gov/pubmed/24790587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/876363
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