Progression-free survival as a surrogate endpoint for overall survival in glioblastoma: a literature-based meta-analysis from 91 trials

BACKGROUND: The aim of this study was to determine correlations between progression-free survival (PFS) and the objective response rate (ORR) with overall survival (OS) in glioblastoma and to evaluate their potential use as surrogates for OS. METHOD: Published glioblastoma trials reporting OS and OR...

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Bibliographic Details
Main Authors: Han, Kelong, Ren, Melanie, Wick, Wolfgang, Abrey, Lauren, Das, Asha, Jin, Jin, Reardon, David A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Clinical Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984546/
https://ncbi.nlm.nih.gov/pubmed/24335699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not236
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