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Branched-chain amino acids inhibit the TGF-beta-induced down-regulation of taurine biosynthetic enzyme cysteine dioxygenase in HepG2 cells

Taurine deficiency has been suggested to contribute to the pathogenesis and complications of advanced hepatic diseases. The molecular basis for a low level of taurine associated with hepatic failure is largely unknown. Using carbon tetrachloride (CCl(4))-induced cirrhotic rat model, we found that th...

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Autores principales: Hagiwara, Asami, Ishizaki, Sonoko, Takehana, Kenji, Fujitani, Shoji, Sonaka, Ichiro, Satsu, Hideo, Shimizu, Makoto
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Vienna 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984414/
https://ncbi.nlm.nih.gov/pubmed/24553827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-014-1693-3
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