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Single Nucleotide Polymorphisms interact to affect ADH7 transcription

BACKGROUND: The class IV alcohol dehydrogenase (ADH7, µ-ADH, σ-ADH) is important in the metabolism of ethanol and retinol. ADH7 is the only ADH not expressed in liver, instead being expressed mainly in the upper gastro-intestinal tract. Genome wide studies have identified significant associations be...

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Autori principali: Jairam, Sowmya, Edenberg, Howard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984380/
https://ncbi.nlm.nih.gov/pubmed/24512552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12340
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