Detection and replication of epistasis influencing transcription in humans

Epistasis is the phenomenon whereby one polymorphism’s effect on a trait depends on other polymorphisms present in the genome. The extent to which epistasis influences complex traits(1) and contributes to their variation(2,3) is a fundamental question in evolution and human genetics. Though often de...

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Detalhes bibliográficos
Main Authors: Hemani, Gibran, Shakhbazov, Konstantin, Westra, Harm-Jan, Esko, Tonu, Henders, Anjali K., McRae, Allan F., Yang, Jian, Gibson, Greg, Martin, Nicholas G., Metspalu, Andres, Franke, Lude, Montgomery, Grant W., Visscher, Peter M, Powell, Joseph E
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984375/
https://ncbi.nlm.nih.gov/pubmed/24572353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13005
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