Direct measurement of local oxygen concentration in the bone marrow of live animals

Characterizing how the microenvironment, or niche, regulates stem cell activity is central to understanding stem cell biology and to developing strategies for therapeutic manipulation of stem cells(1). Low oxygen tension (hypoxia) is commonly thought to be a shared niche characteristic in maintainin...

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Detalhes bibliográficos
Main Authors: Spencer, Joel A., Ferraro, Francesca, Roussakis, Emmanuel, Klein, Alyssa, Wu, Juwell, Runnels, Judith M., Zaher, Walid, Mortensen, Luke J., Alt, Clemens, Turcotte, Raphaël, Yusuf, Rushdia, Côté, Daniel, Vinogradov, Sergei A., Scadden, David T., Lin, Charles P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984353/
https://ncbi.nlm.nih.gov/pubmed/24590072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13034
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