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Evaluation of human pancreatic RNase as effector molecule in a therapeutic antibody platform
Human antibody-ribonuclease (RNase) fusion proteins, referred to as immunoRNases, have been proposed as an alternative to heterologous immunotoxins, without their immunogenicity and unspecific toxicity issues. In this study, we investigated if human pancreatic RNase will be suitable as effector comp...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3984326/ https://ncbi.nlm.nih.gov/pubmed/24492302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27830 |
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