Evolution of the F-Box Gene Family in Euarchontoglires: Gene Number Variation and Selection Patterns

F-box proteins are substrate adaptors used by the SKP1–CUL1–F-box protein (SCF) complex, a type of E3 ubiquitin ligase complex in the ubiquitin proteasome system (UPS). SCF-mediated ubiquitylation regulates proteolysis of hundreds of cellular proteins involved in key signaling and disease systems. H...

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Bibliographic Details
Main Authors: Wang, Ailan, Fu, Mingchuan, Jiang, Xiaoqian, Mao, Yuanhui, Li, Xiangchen, Tao, Shiheng
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984280/
https://ncbi.nlm.nih.gov/pubmed/24727786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094899
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