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Evolution of the F-Box Gene Family in Euarchontoglires: Gene Number Variation and Selection Patterns
F-box proteins are substrate adaptors used by the SKP1–CUL1–F-box protein (SCF) complex, a type of E3 ubiquitin ligase complex in the ubiquitin proteasome system (UPS). SCF-mediated ubiquitylation regulates proteolysis of hundreds of cellular proteins involved in key signaling and disease systems. H...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3984280/ https://ncbi.nlm.nih.gov/pubmed/24727786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094899 |
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