Pseudosubstrate sequence may not be critical for autoinhibition of smooth muscle myosin light chain kinase.

It has been hypothesized that basic residues in the autoinhibitory region of myosin light chain (MLC) kinase, which resemble the substrate sequence, interact with the catalytic core via charge interaction and thus inhibit the kinase activity (pseudosubstrate inhibitory hypothesis). In the present st...

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Pubblicato in:	EMBO J
Autori principali:	Tanaka, M, Ikebe, R, Matsuura, M, Ikebe, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398402/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7796810/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07283.x
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