A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors.

Cytokines manifest their function through alteration of gene expression. However, target genes for signals from cytokine receptors are largely unknown. We therefore searched for immediate-early cytokine-responsive genes and isolated a novel gene, CIS (cytokine inducible SH2-containing protein) which...

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Bibliographic Details
Main Authors: Yoshimura, A, Ohkubo, T, Kiguchi, T, Jenkins, N A, Gilbert, D J, Copeland, N G, Hara, T, Miyajima, A
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC398400/
https://ncbi.nlm.nih.gov/pubmed/7796808
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