A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors.

Cytokines manifest their function through alteration of gene expression. However, target genes for signals from cytokine receptors are largely unknown. We therefore searched for immediate-early cytokine-responsive genes and isolated a novel gene, CIS (cytokine inducible SH2-containing protein) which...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Yoshimura, A, Ohkubo, T, Kiguchi, T, Jenkins, N A, Gilbert, D J, Copeland, N G, Hara, T, Miyajima, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398400/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7796808/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07281.x
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