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The long non-coding RNA Paupar regulates the expression of both local and distal genes

Although some long noncoding RNAs (lncRNAs) have been shown to regulate gene expression in cis, it remains unclear whether lncRNAs can directly regulate transcription in trans by interacting with chromatin genome-wide independently of their sites of synthesis. Here, we describe the genomically local...

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Detalhes bibliográficos
Main Authors: Vance, Keith W, Sansom, Stephen N, Lee, Sheena, Chalei, Vladislava, Kong, Lesheng, Cooper, Sarah E, Oliver, Peter L, Ponting, Chris P
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983687/
https://ncbi.nlm.nih.gov/pubmed/24488179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201386225
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