Progression of human breast cancers to the metastatic state is linked to hydroxyl radical-induced DNA damage.

Hydroxyl radical damage in metastatic tumor DNA was elucidated in women with breast cancer, and a comparison was made with nonmetastatic tumor DNA. The damage was identified by using statistical models of modified base and Fourier transform-infrared spectral data. The modified base models revealed a...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Malins, D C, Polissar, N L, Gunselman, S J
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39836/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8637913/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.6.2557
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