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Imaging Evaluation of 5HT(2C) Agonists, [(11)C]WAY-163909 and [(11)C]Vabicaserin, Formed by Pictet–Spengler Cyclization

[Image: see text] The serotonin subtype 2C (5HT(2C)) receptor is an emerging and promising drug target to treat several disorders of the human central nervous system. In this current report, two potent and selective 5HT(2C) full agonists, WAY-163909 (2) and vabicaserin (3), were radiolabeled with ca...

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Main Authors: Neelamegam, Ramesh, Hellenbrand, Tim, Schroeder, Frederick A., Wang, Changning, Hooker, Jacob M.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2014
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983360/
https://ncbi.nlm.nih.gov/pubmed/24491146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401802f
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