Probing Tertiary Structure of Proteins Using Single Trp Mutations with Circular Dichroism at Low Temperature

[Image: see text] Trp is the most spectroscopically informative aromatic amino acid of proteins. However, the near-UV circular dichroism (CD) spectrum of Trp is complicated because the intensity and sign of (1)L(a) and (1)L(b) bands vary independently. To resolve vibronic structure and gain site-spe...

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Autors principals: Gasymov, Oktay K., Abduragimov, Adil R., Glasgow, Ben J.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983331/
https://ncbi.nlm.nih.gov/pubmed/24404774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp4120145
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