The influence of the 2-amino group of guanine on DNA conformation. Uranyl and DNase I probing of inosine/diaminopurine substituted DNA.

The conformation of the DNA helix is supposed to be a critical element in site-specific recognition by ligands both large and small. Groove width is one important measure of the conformation which varies with the local nucleotide composition, perhaps because of the presence of a purine 2-amino group...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Bailly, C, Møllegaard, N E, Nielsen, P E, Waring, M J
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7744018/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07204.x
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