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Gonadotropin-Releasing Hormone Agonists Sensitize, and Resensitize, Prostate Cancer Cells to Docetaxel in a p53-Dependent Manner

Gonadotropin-releasing hormone (GnRH) receptors are expressed in prostate cancer, specifically in the most aggressive stage of the tumor (castration-resistant prostate cancer, CRPC) for which the standard treatment, docetaxel-based chemotherapy, can only improve the median survival time by few month...

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Detalhes bibliográficos
Main Authors: Moretti, Roberta M., Marelli, Marina Montagnani, Taylor, Deanne M., Martini, Paolo G. V., Marzagalli, Monica, Limonta, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983111/
https://ncbi.nlm.nih.gov/pubmed/24722580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093713
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