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Efficient Separations of Intact Proteins Using Slip-Flow with Nano-Liquid Chromatography–Mass Spectrometry
[Image: see text] A capillary with a pulled tip, densely packed with silica particles of 0.47 μm in diameter, is shown to provide higher peak capacity and sensitivity in the separation of intact proteins by reversed-phase liquid chromatography–mass spectrometry (LC–MS). For a C18 bonded phase, slip...
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| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2014
|
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982985/ https://ncbi.nlm.nih.gov/pubmed/24383398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac403233d |
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