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A combination treatment with DNA methyltransferase inhibitors and suramin decreases invasiveness of breast cancer cells

The treatment of patients with invasive breast cancer remains a major issue because of the acquisition of drug resistance to conventional chemotherapy. Here we propose a new therapeutic strategy by combining DNA methyltransferase inhibitors (DMTIs) with suramin. Cytotoxic effects of suramin or combi...

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Bibliografische gegevens
Hoofdauteurs: Borges, Sahra, Döppler, Heike R., Storz, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982927/
https://ncbi.nlm.nih.gov/pubmed/24510012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-2857-2
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