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Aquaporin-4 Deletion in Mice Reduces Encephalopathy and Brain Edema in Experimental Acute Liver Failure

Brain edema and associated astrocyte swelling leading to increased intracranial pressure are hallmarks of acute liver failure (ALF). Elevated blood and brain levels of ammonia have been implicated in the development of brain edema in ALF. Cultured astrocytes treated with ammonia have been shown to u...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rama Rao, Kakulavarapu V., Verkman, A. S., Curtis, Kevin M., Norenberg, Michael D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982919/
https://ncbi.nlm.nih.gov/pubmed/24321433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.11.018
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