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Aquaporin-4 Deletion in Mice Reduces Encephalopathy and Brain Edema in Experimental Acute Liver Failure

Brain edema and associated astrocyte swelling leading to increased intracranial pressure are hallmarks of acute liver failure (ALF). Elevated blood and brain levels of ammonia have been implicated in the development of brain edema in ALF. Cultured astrocytes treated with ammonia have been shown to u...

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Detalhes bibliográficos
Main Authors: Rama Rao, Kakulavarapu V., Verkman, A. S., Curtis, Kevin M., Norenberg, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982919/
https://ncbi.nlm.nih.gov/pubmed/24321433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.11.018
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