Whole-Genome Sequencing Demonstrates That Fidaxomicin Is Superior to Vancomycin for Preventing Reinfection and Relapse of Infection With Clostridium difficile

Whole-genome sequencing was used to determine whether the reductions in recurrence of Clostridium difficile infection observed with fidaxomicin in pivotal phase 3 trials occurred by preventing relapse of the same infection, by preventing reinfection with a new strain, or by preventing both outcomes....

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Bibliographic Details
Main Authors: Eyre, David W., Babakhani, Farah, Griffiths, David, Seddon, Jaime, Del Ojo Elias, Carlos, Gorbach, Sherwood L., Peto, Tim E. A., Crook, Derrick W., Walker, A. Sarah
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982846/
https://ncbi.nlm.nih.gov/pubmed/24218500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit598
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