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Enhancing the Power to Detect Low-Frequency Variants in Genome-Wide Screens
In genetic association studies a conventional test statistic is proportional to the correlation coefficient between the trait and the variant, with the result that it lacks power to detect association for low-frequency variants. Considering the link between the conventional association test statisti...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Genetics Society of America
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982702/ https://ncbi.nlm.nih.gov/pubmed/24496013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.160739 |
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