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Degradation of Centromeric Histone H3 Variant Cse4 Requires the Fpr3 Peptidyl-prolyl Cis–Trans Isomerase
The centromeric histone H3 variant Cse4 in Saccharomyces cerevisiae is polyubiquitylated and degraded in a proteasome-dependent manner. We report here that the proline isomerase Fpr3 regulates Cse4 proteolysis. Structural change in Cse4 by Fpr3 might be important for the interaction between Cse4 and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Genetics Society of America
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982699/ https://ncbi.nlm.nih.gov/pubmed/24514906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.161224 |
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