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Heterochromatin Position Effects on Circularized Sex Chromosomes Cause Filicidal Embryonic Lethality in Drosophila melanogaster

Some circularized X-Y chromosomes in Drosophila melanogaster are mitotically unstable and induce early embryonic lethality, but the genetic basis is unknown. Our experiments suggest that a large region of X-linked satellite DNA causes anaphase bridges and lethality when placed into a new heterochrom...

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Detalhes bibliográficos
Main Authors: Ferree, Patrick M., Gomez, Karina, Rominger, Peter, Howard, Dagnie, Kornfeld, Hannah, Barbash, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982693/
https://ncbi.nlm.nih.gov/pubmed/24478337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.161075
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