Synthesis of fluorescent analogs of relaxin family peptides and their preliminary in vitro and in vivo characterization

Relaxin, a heterodimeric polypeptide hormone, is a key regulator of collagen metabolism and multiple vascular control pathways in humans and rodents. Its actions are mediated via its cognate G-protein-coupled receptor, RXFP1 although it also “pharmacologically” activates RXFP2, the receptor for the...

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Autori principali: Chan, Linda J., Smith, Craig M., Chua, Berenice E., Lin, Feng, Bathgate, Ross A. D., Separovic, Frances, Gundlach, Andrew L., Hossain, Mohammed Akhter, Wade, John D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982560/
https://ncbi.nlm.nih.gov/pubmed/24790958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2013.00030
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