NK-lysin, a novel effector peptide of cytotoxic T and NK cells. Structure and cDNA cloning of the porcine form, induction by interleukin 2, antibacterial and antitumour activity.

A 78 residue antimicrobial, basic peptide, NK-lysin, with three intrachain disulfide bonds was purified from pig small intestine and characterized. A corresponding clone was isolated from a porcine bone marrow cDNA library. The 780 bp DNA sequence had a reading frame of 129 amino acids which corresp...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Andersson, M, Gunne, H, Agerberth, B, Boman, A, Bergman, T, Sillard, R, Jörnvall, H, Mutt, V, Olsson, B, Wigzell, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398254/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7737114/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07150.x
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