Mice lacking glial fibrillary acidic protein display astrocytes devoid of intermediate filaments but develop and reproduce normally.

Glial fibrillary acidic protein (GFAP) is the main component of the intermediate filaments in cells of astroglial lineage, including astrocytes in the CNS, nonmyelin forming Schwann cells and enteric glia. To address the function of GFAP in vivo, we have disrupted the GFAP gene in mice via targeted...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Pekny, M, Levéen, P, Pekna, M, Eliasson, C, Berthold, C H, Westermark, B, Betsholtz, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398251/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7737111/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07147.x
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