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Recombinant AAV as a Platform for Translating the Therapeutic Potential of RNA Interference

RNA interference has become a ubiquitous biological tool, and is being harnessed for therapeutic purposes as well. Therapeutic posttranscriptional gene silencing takes advantage of the endogenous RNAi pathway through delivery of either chemically synthesized siRNAs, or transgenes expressing hairpin-...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Borel, Florie, Kay, Mark A, Mueller, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982504/
https://ncbi.nlm.nih.gov/pubmed/24352214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.285
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