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Recombinant AAV as a Platform for Translating the Therapeutic Potential of RNA Interference

RNA interference has become a ubiquitous biological tool, and is being harnessed for therapeutic purposes as well. Therapeutic posttranscriptional gene silencing takes advantage of the endogenous RNAi pathway through delivery of either chemically synthesized siRNAs, or transgenes expressing hairpin-...

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Bibliografiske detaljer
Main Authors: Borel, Florie, Kay, Mark A, Mueller, Christian
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982504/
https://ncbi.nlm.nih.gov/pubmed/24352214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.285
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