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Targeting Estrogen-Related Receptor Alpha Inhibits Epithelial-to-Mesenchymal Transition and Stem Cell Properties of Ovarian Cancer Cells

Epithelial–mesenchymal transition represents a key event in cancer progression and has emerged as a promising anticancer target. Estrogen-related receptor alpha (ERRα) is frequently elevated in advanced-stage ovarian cancer, but its potential role in tumor progression is not known. Here we show that...

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Bibliografiske detaljer
Main Authors: Lam, Sophia SN, Mak, Abby SC, Yam, Judy WP, Cheung, Annie NY, Ngan, Hextan YS, Wong, Alice ST
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982489/
https://ncbi.nlm.nih.gov/pubmed/24419103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.1
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