Skin Electroporation of a Plasmid Encoding hCAP-18/LL-37 Host Defense Peptide Promotes Wound Healing

Host defense peptides, in particular LL-37, are emerging as potential therapeutics for promoting wound healing and inhibiting bacterial growth. However, effective delivery of the LL-37 peptide remains limiting. We hypothesized that skin-targeted electroporation of a plasmid encoding hCAP-18/LL-37 wo...

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Detalhes bibliográficos
Main Authors: Steinstraesser, Lars, Lam, Martin C, Jacobsen, Frank, Porporato, Paolo E, Chereddy, Kiran Kumar, Becerikli, Mustafa, Stricker, Ingo, Hancock, Robert EW, Lehnhardt, Marcus, Sonveaux, Pierre, Préat, Véronique, Vandermeulen, Gaëlle
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982484/
https://ncbi.nlm.nih.gov/pubmed/24394186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.258
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