Inhibition of HIV-1 Tat-mediated LTR transactivation and HIV-1 infection by anti-Tat single chain intrabodies.

Genes encoding the rearranged immunoglobulin heavy and light chain variable regions of anti-HIV-1 Tat, exon 1 or exon 2 specific monoclonal antibodies have been used to construct single chain intracellular antibodies 'intrabodies' for expression in the cytoplasm of mammalian cells. These a...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Mhashilkar, A M, Bagley, J, Chen, S Y, Szilvay, A M, Helland, D G, Marasco, W A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398241/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7537216/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07140.x
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