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The putative tRNA 2-thiouridine synthetase Ncs6 is an essential sulfur carrier in Methanococcus maripaludis

Thiolation of carbon-2 of uridine located in the first position of the anticodons of tRNA(Gln)(UUG), tRNA(Glu)(UUC), and tRNA(Lys)(UUU) is a conserved RNA modification event requiring the 2-thiouridine synthetase Ncs6/Ctu1 in archaea and eukaryotes. Ncs6/Ctu1 activates uridine by adenylation, but it...

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Autors principals: Liu, Yuchen, Long, Feng, Wang, Liangliang, Söll, Dieter, Whitman, William B.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982309/
https://ncbi.nlm.nih.gov/pubmed/24530533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.01.065
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