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Hippo signaling regulates Microprocessor and links cell density-dependent miRNA biogenesis to cancer
Global downregulation of microRNAs (miRNAs) is commonly observed in human cancers and can have a causative role in tumorigenesis. The mechanisms responsible for this phenomenon remain poorly understood. Here we show that YAP, the downstream target of the tumor-suppressive Hippo signaling pathway reg...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982296/ https://ncbi.nlm.nih.gov/pubmed/24581491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.12.043 |
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