Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53.

Epstein-Barr virus (EBV) efficiently converts resting human B cells into actively cycling, immortal, lymphoblastoid cell lines (LCLs). Here we show that LCLs expressing the full complement of latent viral genes are very sensitive to DNA-damaging agents such as cisplatin. The response includes a rapi...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Allday, M J, Sinclair, A, Parker, G, Crawford, D H, Farrell, P J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7729416/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07124.x
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