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IL-33 stimulates CXCL8/IL-8 secretion in goblet cells but not normally differentiated airway cells

BACKGROUND: IL-13, a helper T-cell type2 (Th2) cytokine transforms cultured airway epithelial cells to goblet cells and this is not inhibited by corticosteroids. IL-33 stimulates Th2 cytokines and is highly expressed in airways of persons with asthma. The effect of IL-33 on goblet cell differentiati...

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Detalhes bibliográficos
Main Authors: Tanabe, Tsuyoshi, Shimokawaji, Tadasuke, Kanoh, Soichiro, Rubin, Bruce K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982145/
https://ncbi.nlm.nih.gov/pubmed/24479526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12283
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