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Electrostimulation to reduce synaptic scaling driven progression of Alzheimer's disease

Cell death and synapse dysfunction are two likely causes of cognitive decline in AD. As cells die and synapses lose their drive, remaining cells suffer an initial decrease in activity. Neuronal homeostatic synaptic scaling then provides a feedback mechanism to restore activity. This homeostatic mech...

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Detalhes bibliográficos
Main Authors: Rowan, Mark S., Neymotin, Samuel A., Lytton, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982056/
https://ncbi.nlm.nih.gov/pubmed/24765074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncom.2014.00039
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