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Lesions of the Medial Striatum in Monkeys Produce Perseverative Impairments during Reversal Learning Similar to Those Produced by Lesions of the Orbitofrontal Cortex

The ability to switch responding between two visual stimuli based on their changing relationship with reward is dependent on the orbitofrontal cortex (OFC). OFC lesions in humans, monkeys, and rats disrupt performance on a common test of this ability, the visual serial discrimination reversal task....

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Autors principals: Clarke, Hannah F., Robbins, Trevor W., Roberts, Angela C.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981993/
https://ncbi.nlm.nih.gov/pubmed/18945905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1521-08.2008
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