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Label-free in vivo imaging of myelinated axons in health and disease with spectral confocal reflectance microscopy

We report a new technique for high-resolution in vivo imaging of myelinated axons in the brain, spinal cord and peripheral nerve that requires no fluorescent labeling. This method, based on spectral confocal reflectance microscopy (SCoRe), uses a conventional laser scanning confocal system to genera...

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Detalhes bibliográficos
Main Authors: Schain, Aaron J., Hill, Robert A., Grutzendler, Jaime
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981936/
https://ncbi.nlm.nih.gov/pubmed/24681598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3495
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