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Long-term function of islets encapsulated in a re-designed alginate microcapsule construct in omentum pouches of immune-competent diabetic rats

OBJECTIVES: Our study aim was to determine encapsulated islet graft viability in an omentum pouch and the effect of FGF-1 released from our redesigned alginate microcapsules on the function of the graft. METHODS: Isolated rat islets were encapsulated in an inner core made with 1.5% low-viscosity hig...

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Detalhes bibliográficos
Main Authors: Pareta, Rajesh, McQuilling, John P, Sittadjody, Sivanandane, Jenkins, Randy, Bowden, Stephen, Orlando, Giuseppe, Farney, Alan C, Brey, Eric M, Opara, Emmanuel C
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981909/
https://ncbi.nlm.nih.gov/pubmed/24681880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000107
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