Antiviral Activity of Genital Tract Secretions following Oral or Topical Tenofovir Pre-exposure Prophylaxis for HIV-1

BACKGROUND: Surrogate markers of HIV-1 pre-exposure prophylaxis (PrEP) and microbicide efficacy are needed. One potential surrogate is the antiviral activity in cervicovaginal lavage (CVL) after exposure to candidate products. We measured CVL antiviral activity in women using oral or vaginal tenofov...

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Autori principali: Herold, Betsy C., Dezzutti, Charlene S., Richardson, Barbra A., Marrazzo, Jeanne, Mesquita, Pedro M.M., Carpenter, Colleen, Huber, Ashley, Louissaint, Nicolette, Marzinke, Mark A., Hillier, Sharon L., Hendrix, Craig W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981887/
https://ncbi.nlm.nih.gov/pubmed/24457633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000110
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