Persistence of Th1/Tc1 responses one year after tetravalent dengue vaccination in adults and adolescents in Singapore

To characterize the cell mediated immunity (CMI) induced by the investigational CYD tetravalent dengue vaccine (TDV), we developed a whole-blood, intracellular cytokine staining (ICS) assay and a multiplex assay, each requiring 3 mL of blood. We assessed CMI before and 28 d after a first and third i...

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Auteurs principaux: Harenberg, Anke, Begue, Sarah, Mamessier, Audrey, Gimenez-Fourage, Sophie, Ching Seah, Ching, Wei Liang, Ai, Li Ng, Jun, Yun Toh, Xue, Archuleta, Sophia, Wilder-Smith, Annelies, Shek, Lynette P, Wartel-Tram, Anh, Bouckenooghe, Alain, Lang, Jean, Crevat, Denis, Caillet, Catherine, Guy, Bruno
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2013
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Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981840/
https://ncbi.nlm.nih.gov/pubmed/23839107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25562
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