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Persistence of Th1/Tc1 responses one year after tetravalent dengue vaccination in adults and adolescents in Singapore

To characterize the cell mediated immunity (CMI) induced by the investigational CYD tetravalent dengue vaccine (TDV), we developed a whole-blood, intracellular cytokine staining (ICS) assay and a multiplex assay, each requiring 3 mL of blood. We assessed CMI before and 28 d after a first and third i...

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Autori principali: Harenberg, Anke, Begue, Sarah, Mamessier, Audrey, Gimenez-Fourage, Sophie, Ching Seah, Ching, Wei Liang, Ai, Li Ng, Jun, Yun Toh, Xue, Archuleta, Sophia, Wilder-Smith, Annelies, Shek, Lynette P, Wartel-Tram, Anh, Bouckenooghe, Alain, Lang, Jean, Crevat, Denis, Caillet, Catherine, Guy, Bruno
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981840/
https://ncbi.nlm.nih.gov/pubmed/23839107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25562
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